Pain Management Nursing Practice Exam 2025 – Complete Preparation Guide

A transdermal fentanyl patch is designed to deliver a consistent dose of medication across the skin and into the bloodstream over a specified period. For effective absorption of the medication, adequate subcutaneous tissue is necessary. In patients who weigh less than 100 pounds, especially those with low body fat or insufficient subcutaneous tissue, the absorption of fentanyl may be compromised.

Low body weight can affect the pharmacokinetics of drugs delivered through the skin. If there is not enough subcutaneous fat, the patch may not adhere properly or may not be able to deliver the medication efficiently into the systemic circulation. The transdermal system relies on a certain depth of tissue for the medication to be absorbed effectively; thus, insufficient subcutaneous tissue can lead to inadequate pain relief.

This understanding emphasizes the importance of considering a patient’s body weight and composition when prescribing transdermal medications to ensure they receive an effective and safe dose tailored to their physiological needs.